Afterburn may refer to:
Excess post-exercise oxygen consumption, the burning of calories after vigorous exercise
Back-fire, an unintended explosion produced by a vehicle's engine
Afterburn (psychotherapy), a psychological term used during the application of psychotherapy
Afterburn (film), a film starring Laura Dern
Afterburner, an optional component in jet engines
Agnelli & Nelson, who write and produce dance music, under the name Afterburn, among others
Afterburn (roller coaster), a Bolliger & Mabillard coaster at Carowinds
WWE Afterburn, a television show produced by World Wrestling Entertainment